NFκB transcription factors are homodimers or heterodimers of NFκB1 (p50), NFκB2 (p52), RelA (p65), RelB, or cREL [39], and have been widely reported to participate in tumor initiation, cell proliferation, apoptosis, chemoresistance, and the EMT [28, 40-42]. Here, REL is linked to neoplasm.