In light of several literature reports on the efficacy of mTOR inhibitors in GCV-resistant CMV infection [10] our patient's immunosuppressive regimen was modified with the introduction of everolimus (trough level of 3–8 ng/mL) and a further reduction of tacrolimus dosage (trough level of 1–3 ng/mL). This evidence concerns the gene MTOR and cytomegalovirus infection.