RELN and psychiatric disorder: These results were independently replicated by several research groups (Fatemi et al., 2000; Eastwood and Harrison, 2003; Knable et al., 2004; Torrey et al., 2005; Habl et al., 2012), opening the field for subsequent investigation of how reelin dysregulation might be operative in the pathogenesis and/or pathophysiology of multiple psychiatric disorders.