S100B and schizophrenia: Here, we conducted a systematic and quantitative meta-analysis of changes in serum S100B in schizophrenia, which extends former meta-analyses on this issue (Schroeter et al., 2003, 2009; Schroeter and Steiner, 2009; Aleksovska et al., 2014) by including further studies and accordingly, increasing statistical power and evidence.