Another study on cytokines in NMO did not find an increase in serum or CSF levels of IL-17 but did find an increased level of other Th17-related cytokines, notably IL-6 [52], which is a proinflammatory cytokine that increases the survival of plasmablasts capable of producing anti-AQP4-IgG and is also involved in the development of Th17 cells, which can also support B cell development and induce further tissue injury [62]. The gene discussed is AQP4; the disease is neuromyelitis optica.