In the stepwise forward regression analysis triglycerides, insulin, waist circumference, diabetes duration, pyrilinks and BB treatment remained significantly correlated with PAI-1 after adjusting for age and BMI, but the correlation between PAI-1 and hip BMD was no longer significant as was the case with the correlation between PAI-1 and ACEi/ARB therapy (Table 3). Here, SERPINE1 is linked to diabetes mellitus.