MRC1 and hepatocellular carcinoma: Furthermore, multivariate Cox’s regression analysis, after backward stepwise variable selections, suggested that apart from tumor size, tumor differentiation, and vascular invasion, infiltration of CD86+ and CD206+ TAMs remained as the independent prognostic factors in HCC patients for both OS (HR = 2.178, p = 0.040 and HR = 1.584, p = 0.027) and TTR (HR = 1.810, p = 0.006 and HR = 1.872, p = 0.030).