Of note, the ratio of ++:Δ+:ΔΔ embryos, 7:10:5, was near Mendelian, consistent with prior evaluation of Cebpa ORF +/+ vs +/- vs -/- newborns [19] and with the idea that neonatal lethality due to sepsis accounts for the markedly reduced numbers of Enh(f/f);CMV-Cre (ΔΔ) or Enh(f/f);Vav-Cre mice obtained upon weaning. Here, VAV1 is linked to Sepsis.