Our results show that the mean of CTNNB1's GPVs in the APC mutant cell lines is 20% of that in the APC wild-type cell lines (P value <10–7), and CTNNB1 has significantly higher level of expression in APC mutant cancer cell lines than in wide-type cell lines (P value = 0.015, fold-change = 1.52). Here, APC is linked to cancer.