As shown in Table 4, the incidence of daytime sleepiness (ESS >10) was significantly greater in AD patients with the IL-1β TT genotype than in those with the CT or CC genotype (58.8% vs. 47.4% and 20.0%, p = 0.029) and greater in patients with the T allele than in those with the C allele (54.7% vs. 37.9, p = 0.012). This evidence concerns the gene IL1B and Alzheimer disease.