In this study we looked for association between 14 single nucleotide polymorphisms (SNPs) in 7 of the top GWAS genes (TCF7L2, CDKAL1, HHEX, IGF2BP2, KCNJ11, PPARG and CAPN10) and risk of T2D in Sudan. The gene discussed is TCF7L2; the disease is type 2 diabetes mellitus.