In the present study, we investigated a possible association between T2D in Sudan and SNPs from 6 genes (PPARG, IGF2BP2, CDKAL1, HHEX, TCF7L2, and KCNJ11) that had achieved genome-wide significance in multiple GWAS undertaken across different ethnicities [31], in addition to CAPN10 which had been shown to be associated with T2D in a large study of Caucasians [26] and in Tunisia [27]. This evidence concerns the gene KCNJ11 and type 2 diabetes mellitus.