NPC1 and nasopharyngeal carcinoma: Molecular genetic testing revealed a compound heterozygous mutant NP-C genotype comprising two previously described mutations in the NPC1 gene, one in exon 8 (c.1133T>C [V378A]) and one in exon 13 (c.1990G>A [V664M]), establishing the diagnosis of NPC [1], [5].