MYB and chronic myelogenous leukemia, BCR-ABL1 positive: In fact, in all tested CML cell lines (K562, LAMA-84, BV-173) and in primary cells from CML patients coinciding c-MYB and ESPL1/Separase expression levels irrespective to therapeutic treatment (IM) and silencing (siRNA) conditions (Figs. 1, 2 and 3) were observed.