ANGPT2 and asthma: For the whole asthma group a modest correlation between Angiopoietin-2 serum levels and number of asthma exacerbations was found (R = 0.21; p < 0.05) (Fig. 2a), and among patients with SRA Angiopoietin-2 levels correlated with the number of emergency visits due to severe asthma exacerbation (R = 0.24; p < 0.04) (Fig. 2b) and with the number of hospitalizations (R = 0.21; p < 0.05) (Fig. 2c).