On the basis of the characterization of RNF11 in monocytic cell lines (69), its role in Parkinson's disease (65), its differential expression in neurons and glial cells (70), and our confirmed analysis of the upregulation of miR-19b-3p after JEV infection, we hypothesized that RNF11 may also have a role in inducing the JEV-mediated inflammatory response. Here, RNF11 is linked to Parkinson disease.