There were significant differences between group mean scores in both the primary group analysis (Alzheimer’s disease, DLB, FTLD and control) and the subgroup analysis (early and late-onset Alzheimer’s disease, DLB, FTLD-Tau, FTLD-TDP43, younger and older controls) for all visual rating scales. This evidence concerns the gene MAPT and early-onset autosomal dominant Alzheimer disease.