The FTLD-Tau group had significantly higher scores than the early-onset Alzheimer’s disease and DLB groups in all but the PA scale (P< 0.05), and the late-onset Alzheimer’s disease group in the frontal scales only (P< 0.001 AC,P< 0.05 OF, FI). The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.