For example, β-eudesmol (a compound in Atractylodes macrocephala, Saposhnikovia divaricata, Ephedra sinica and Zingiber officinale) was a potential therapy in mast cell-mediated inflammation and an inhibitor of Cytochrome P450 2C9 which accepted responsibility for the metabolism of NSAID55; Camphor (a compound in Cinnamomum cassia, Ephedra sinica and Zingiber officinale) has been used in clinical trial for RA treatment for a long time56; β-sitosterol can effect as an anti-inflammation through significantly suppressing the T-cell immune response57. Here, CYP2C9 is linked to rheumatoid arthritis.