IL6 and CAPN5-related vitreoretinopathy: Consistent with the aforementioned study, Canataroglu et al[26] found that the levels of IL-6 and IL-8 were elevated in vitreous of patients with PDR or with proliferative vitreoretinopathy (PVR) and suggested that IL-6 and IL-8 may play an important role in the pathogenesis of PDR and PVR.