VWF and acute kidney injury: Van Geet et al. found an elevation in markers of fibrinolysis (t-plasminogen activator, u-plasminogen activator, and D-dimer) but no difference in PT, aPTT, factor VIII, and von Willebrand factor antigen level in an analysis of 24 D+HUS patients compared to 15 patients with acute renal failure as controls [17].