Survival rates of HepG2 cells were 107.5%, 99.7%, and 100.1%, and survival rates of Hep3B cells were 107.5%, 99.7% and 100.1% (p > 0.05) at 0, 48, and 72 hours after rAdV-ASPP2 infection, respectively (Figure 2D). The gene discussed is TP53BP2; the disease is infection.