Inactivation of NF-κB p65 by PDTC significantly inhibited α-SMA and FAP expression in GC-MSC (Figure 6E, 6F), and greatly suppressed the capacity of GC-MSC to promote gastric cancer cell HGC-27 colony formation, migration and invasion (Figure 6G-6I). The gene discussed is NFKB1; the disease is gastric cancer.