Extracellular calgranulin B was absorbed in the cytoplasm of all three colon cancer cell lines tested (SNU-81, HCT-116, SNU-C4), but not others (gastric cancer, SNU-484; ovarian cancer, SNU-840; cervical cancer, HeLa) at 72 h post treatment. This evidence concerns the gene S100A9 and colonic neoplasm.