Notably, tumor depth was significantly related to FGFR2 IHC positivity in the multivariate logistic analysis (multivariate odds ratio = 4.57; 95% confidence interval 1.99-11.02; P < 0.001, Table 2) [Bonferroni-corrected P < 0.004 (= 0.05/14)]. The gene discussed is FGFR2; the disease is neoplasm.