In the complete GBM cohort, TP53-mutated cases were significantly more likely to carry additional mutations in other genes: 67% (111of 166) while only 51% (167 of 327) of TP53-wild type cases had additional mutations (RR=1.31 [1.13-1.52], p=0.0011). Here, TP53 is linked to glioblastoma.