For example, the mean seizure onset of 5 months old is similar for both Dravet syndrome and SCN8A-related encephalopathy, however, unlike Dravet syndrome the upper age limits in cases due SCN8A can be after one year [1, 4]. The gene discussed is SCN8A; the disease is encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.