TNF and infection: Micedeficient for TNFR1 on myeloid cells rapidly lost weight and succumbed by day 35after infection with M. tuberculosis H37Rv, similar to fully deficientTNFR1 KO mice, while wild-type controls survived the acute phase of infection,and fully TNF deficient mice succumbed even earlier by day 28 (Fig. 2a,b).