Granuloma formation is the result of a structured cell mediated immune responseand is associated with efficient containment of M. tuberculosis growth.The increased lung inflammation in mice lacking the TNF or TNFR1 pathwayprompted us to address the contribution of TNFR1 of myeloid origin in granulomaformation upon M. tuberculosis infection. Here, TNFRSF1A is linked to Granuloma.