Indeed, lungbacterial load and lung weight as indicator of pulmonary inflammation weresignificantly increased in mice reconstituted with TNFR1 KO BM, as compared toWT BM, irrespective of the genotype of the recipient (Fig.1b,c), while transfer of WT BM to TNFR1 KO mice restored thephenotype with no significant difference as compared to WTBM = > WT control mice on day 30post-infection. The gene discussed is TNFRSF1A; the disease is infection.