TIMP1 and non-small cell lung carcinoma: Fourth, anti-invasive and TIMP-1-upregulating properties of AA-5HT and URB597 were confirmed in another lung tumor cell line, H460, as well as in metastatic cells obtained from resection of brain metastasis of a patient with non-small cell lung cancer (NSCLC), indicating the observed effects to be not restricted to one cell line.