As shown in Table 2, multivariate Cox analysis identified five significant prognostic factors, including pathology tumor stage (p = 0.0103), nodal stage (p = 0.0031), EGFR (p = 0.0161), CK5/6 (p = 0.0177), and Ki-67 (p = 0.0468). Here, MKI67 is linked to neoplasm.