According data in the literature, the rate of diagnostic underestimation by corebiopsy for DCIS ranges from 0% to 59%(11,22), and in thepresent study was of 28.57%, while for ADH it ranges from 7% to 88%(11,12,23), and in thepresent study was 50%. This evidence concerns the gene AVP and ductal breast carcinoma in situ.