In addition, CD146 high group were more likely to manifest high AFP level (P = 0.009), vascular invasion (P = 0.016), satellite lesions (P = 0.028), no tumor encapsulation (P = 0.019), poor tumor differentiation (P = 0.006), and higher recurrence (P < 0.001, Table 1). This evidence concerns the gene MCAM and neoplasm.