We demonstrated that ADR treatment induced 2 types of tumor dormancy: 1) an indolent type of dormancy, characterized by the positive/low expression of Ki67; this type of dormancy is maintained through balanced proliferation and death, as these cells keep producing dead cells, whereas the total number of viable cells remains unchanged; and 2) a quiescent type of tumor dormancy that is characterized by lack of Ki67 expression (Ki67−); this type of dormancy is maintained through total cessation of proliferation. Here, MKI67 is linked to neoplasm.