The signal transduction gene lists common to all tested tumor types include signaling by RTKs such as fibroblast growth factor (FGF) receptor family, epidermal growth factor (ErbB) receptor family, platelet-derived growth factor (PDGF) receptor family, vascular endothelial growth factor (VEGF) receptor family, insulin receptor family as well as signaling by G-protein-coupled receptors (GPCR) and Wnt, AKT/mTOR, and RAS/MAPK pathways. The gene discussed is MTOR; the disease is neoplasm.