Carcinomas of the ovary, uterus, and breast, and adenocarcinoma of the colon have higher interaction strengths compared to other tumor types for several anaphase and metaphase-related gene lists such as those involving anaphase promoting complex (APC/C), its inhibitor Emi1, NIMA family kinases, and nuclear mitotic apparatus (NuMA). The gene discussed is FBXO5; the disease is neoplasm.