PADI2 and rheumatoid arthritis: As an empirical example, we focused on PADI2 at 1p36 pointed by multiple miRNAs (miR-4492 at 11q23 and miR-4728-5p at 17q12) in the context of the RA GWAS, as inhibition of this drug target gene is considered to be promising for treatment of autoimmune diseases33.