On the other hand, an isoflavone mixture obtained from C. sinensis was reported to exert beneficial effects on osteoporosis in ovariectomized rats, the effect being attributed to the decrease of alkaline phosphatase activity, TRAP activity, C-terminal crosslinked telopetides of collagen type 1 (CTX), and interferon-γ levels [93]. The gene discussed is ACP5; the disease is osteoporosis.