Even though there are multiple possible explanations for the effects of JZL184 on fear learning, our results and those of Llorente-Berzal27 both contrast recent work demonstrating constitutive DAGLα deletion, which reduces 2-AG levels, also impairs fear extinction.26 Our data also contrast multiple findings indicating JZL184 decreases unconditioned anxiety and stress responses, as described above. Here, DAGLA is linked to Anxiety.