HMGB1 and endometrial carcinoma: It has been shown that overexpression of micro(mi)RNA-218 sensitized paclitaxel resistant endometrial carcinoma cells to paclitaxel by binding to the 3′-UTR of the HMGB1 gene, with downregulation of HMGB1 expression and suppression of HMGB1-mediated autophagy [39].