The hexane extract of C. tamariscifolia (CTH) had the highest cytotoxic activity (IC50 = 2.31 μg/mL), and was further tested in four human tumor (cervical adenocarcinoma HeLa; gastric adenocarcinoma AGS; colorectal adenocarcinoma HCT-15; neuroblastoma SH-SY5Y), and two non-tumor (murine bone marrow stroma S17 and human umbilical vein endothelial HUVEC) cell lines in order to determine its selectivity. This evidence concerns the gene CTH and colorectal adenocarcinoma.