IL1B and epilepsy: The experimental results showed that the role of anti-IL-1β mAb-SPIONs on treatment for epilepsy is not affected by decreased proliferation of astrocytes, implying that astrocytes which affect the development of epilepsy are related to many mechanisms, such as ion channels and water channels, amino acid metabolism of the excitatory, and inhibitory amino acids in the inside and outside of cells, cell factors, and gap junctions.