SO:SL Ratio. The ratio (seeDataset 3) of synaptophysin-positive puncta in the SO to puncta in the SL (Figure 3C andSupplemental Figure S1) was analyzed using a 3×3 univariate ANOVA (age (PND16, PND18, PND20) and training history (HCC, ONL, MWM) as the fixed factors). The gene discussed is SYP; the disease is hepatocellular carcinoma.