Additionally, the SNP rs6259 in the promoter region of SULT1E1 has been associated with increased risk of endometrial cancer (Rebbeck et al., 2006; Hirata et al., 2008), and SNPs *959 G>A and IVS4-1653 T>C with increased recurrence of endometrial cancer (Choi et al., 2005). The gene discussed is SULT1E1; the disease is endometrial cancer.