However, there was no apparent correlation between the LAMP2 peptides and the CSF core biomarkers, Aβ1–42, T- and P-tau with threonine phosphorylation at position 181 (P-tau181), neither in the AD core biomarker profile group (Additional file 3: Figure S17) nor in the control group (Additional file 3: Figure S18). This evidence concerns the gene LAMP2 and Alzheimer disease.