In addition, we thus analysed a different mouse model that is based on the overexpression of platelet-derived growth factor beta (PDGF-B) in cortical NP (see ref. 43 and Fig. 3d), to determine whether the glioma-associated repression of Zfp423 was consistent across different tumour-driving mutations. The gene discussed is ZNF423; the disease is central nervous system cancer.