We evaluated several possible prognostic factors that may influence survival in elderly patients with CRC, including age, underlying disease, TNM stage, grade of tumor differentiation, preoperative CEA level, lymphovascular invasion, perineural invasion, and postoperative complications 28, 29, 30, 31, 32, 33, 34, 35. This evidence concerns the gene CEACAM5 and colorectal carcinoma.