The MAP peptides identified within different proteins (MAP2404c, MAP1,4-α-glucan branching protein and MAP3865c) are characterized by sequence homology with proinsulin (PI) and ZnT8 transmembrane domain; the outcomes of competitivity assays clearly demonstrate their cross-reactivity12, 13 and allow to hypothesize the role of molecular mimicry through which MAP contribution to T1D development may occur. Here, INS is linked to type 1 diabetes mellitus.