Multivariate analysis showed that, in addition to the lymph node metastasis, LATS1 expression might act as an independent prognostic factor for overall survival (OS) (P = 0.017, Table 3) and recurrence-free survival (RFS) (P = 0.026, Table 4) of GC patients. This evidence concerns the gene LATS1 and metastatic malignant neoplasm in the lymph nodes.