In the Burkinabe cohort, isotype IgG responses against GLURP R2 (HR 0.84; 95 % CI 0.73–0.97; p = 0.01) and MSP1 hybrid (HR 0.83; 95 % CI 0.70–0.98; p = 0.03) were significantly associated with reduced risk of clinical malaria after adjusting for age (Table 3). This evidence concerns the gene ATAD1 and malaria.