MCL1 and breast cancer: Indeed, our results demonstrate anti-BC activity in Luminal A-like (MCF-7) and TNBC (MDA MB-231) cells upon both siRNA-mediated downregulation of Mcl-1 (Additional file 1: Figure S3a,b) as well as treatment with EU-5346 (Additional file 1: Figure S3c,d), as evidenced by PARP cleavage (Additional file 1: Figure S3a,c), AlamarBlue® assays (Additional file 1: Figure S3b), and [3H]-thymidine uptake (Additional file 1: Figure S3d).