Neurodegenerative diseases such as Charcot–Marie–Tooth 2A (CMT2A) and dominant optic atrophy (DOA) manifest with degeneration of sensory and motor nerves and optic nerve as a direct consequence of mutations in genes encoding mitochondrial fusion proteins Mfn2 and OPA1, respectively (Chan, 2012). This evidence concerns the gene OPA1 and autosomal dominant optic atrophy.