Several randomized clinical trials have shown, both in Caucasian and Asian population, superior overall response rates (ORRs) and progression free survival (PFS) for patients receiving EGFR-TKIs (Erlotinib, Gefitinib, Afatinib), compared to standard chemotherapy in patients with NSCLC harboring tumors with EGFR activating mutations [9–11]. Here, EGFR is linked to non-small cell lung carcinoma.