CASP8 and malignant colon neoplasm: As shown in Figure 5C, inhibition of caspase-8 almost completely reversed the apoptotic levels of SW1116, SW480 and DLD-1 cells after TSLP stimulation at 100 ng/ml to the baseline levels, and significantly decreased apoptosis of colon cancer cells after TSLP stimulation at 200 ng/ml.